1520s, in Scots law, "act of disabling or wounding a limb," from Middle French mutilation and directly from Late Latin mutilationem (nominative mutilatio), noun of action from past-participle stem of Latin mutilare "to cut or lop off," from mutilus "maimed," which is of uncertain etymology. Of things, "a destroying of unity by damaging or removing a part," from 1630s.