c. 1600, "common to or affecting a whole people," originally and usually, though not etymologically, in reference to diseases, from French épidémique, from épidemié "an epidemic disease," from Medieval Latin epidemia, from Greek epidemia "a stay in a place; prevalence of an epidemic disease" (especially the plague), from epi "among, upon" (see epi-) + dēmos "people, district" (see demotic). Also see -ic.