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The Merck Manual--Second Home Edition logo
 
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Chapter 250. Sexual Dysfunction
Topics: Introduction | Dyspareunia | Vaginismus | Vulvodynia | Decreased Libido | Sexual Arousal Disorder | Orgasmic Disorder
 
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Decreased Libido

Decreased libido is a reduction in the sex drive.

A temporary reduction in sex drive is common, often caused by temporary conditions, such as fatigue. Sex drive that continues to be reduced can distress a woman or her partner.

Sex drive is controlled in part by sex hormones, such as estrogen and testosterone. Fluctuations in the levels of these hormones, which occur monthly and during pregnancy, can affect sex drive. In postmenopausal women, sex drive may be reduced because estrogen levels decrease. Sex drive may also be reduced in women who have had both ovaries removed.

A reduction in sex drive may result from depression, anxiety, stress, or problems in a relationship. Use of certain drugs, including anticonvulsants (see Section 6, Chapter 85), chemotherapy drugs (such as tamoxifen), beta-blockers (see Section 3, Chapter 22), and oral contraceptives, can also reduce the sex drive, as can drinking excessive amounts of alcohol.

The diagnosis is based on the woman's description of the problem. A doctor asks the woman about stress and other lifestyle problems and her sexual and medical history, including use of drugs. Levels of sex hormones may be measured in a blood sample.

Treatment depends on the cause. Drugs that may be contributing are discontinued if possible. If psychologic factors are involved, counseling may be recommended. If the cause is low levels of sex hormones, a low dose of testosterone combined with estrogen may be given by mouth. In addition to increasing sex drive, testosterone may also increase muscle strength, prevent loss of bone density, and improve energy.

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