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The Merck Manual--Second Home Edition logo
 
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Chapter 223. Nose and Throat Cancers
Topics: Introduction | Cancer of the Larynx | Cancer of the Paranasal Sinuses | Cancer of the Nasopharynx | Cancer of the Tonsils
 
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Cancer of the Tonsils

Cancer of the tonsils occurs predominantly in men. It is strongly linked to smoking and alcohol consumption. This cancer often spreads to the lymph nodes in the neck. Cancer of the tonsils occurs most often in people between the ages of 50 and 70.

A sore throat is often the first symptom. Pain usually radiates to the ear on the same side as the affected tonsil. Sometimes, however, a lump in the neck resulting from the cancer's spread to a lymph node (metastasis) may be noticed before any other symptoms. A doctor diagnoses the cancer by performing a biopsy of the tonsil, in which a sample of tissue is removed for examination under a microscope. Evaluation usually includes laryngoscopy (examination of the larynx), bronchoscopy (examination of the lungs), and esophagoscopy (examination of the esophagus). These areas are evaluated because of the high risk of additional cancers being present (up to 10%).

Treatment typically includes radiation therapy and surgery. Certain types of chemotherapy are effective as well, when combined with radiation therapy. Surgery may involve removal of the tumor, lymph nodes in the neck, and part of the jaw. There have been notable advances in the reconstruction used after surgery to remove the cancer, resulting in significant improvements in function and appearance. About 50% of the people survive for at least 5 years after diagnosis, although the exact number depends on the stage of the cancer at the time of treatment.

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