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Genistein is generally more available in fermented soy products, such as tempeh and miso, rather than soy milk or tofu. Supro is a patented soy protein product that has been used in many clinical trials for lowering cholesterol and blood lipids. It contains high amounts of genistein. Many of the soy protein products sold in natural food stores contain supro soy protein. Although there are some encouraging reports on the use of benistein as an anticancer agent, I recommend using whole soy food concentrates rather than isolates such as genistein.
Bovine Cartilage and Shark Cartilage
Both bovine and shark cartilage inhibit angiogenesis when placed in close proximity with cancer cells; they do not prevent anglogenesis in healthy cells. 158,159
As an antitumor and anticancer agent, shark cartilage has received more publicity than any other supplement I can remember. Although I believe it may have some beneficial effects in a few cases, its benefits are limited to inhibiting angiogenesis (and thus metastasis), and I feel at this time that it is overrated. In fact, based on a recent study, Cartilage Technologies, Inc., the manufacturer of a leading brand of shark cartilage, has discontinued the sponsorship of an FDA-supervised clinical trial that was designed to evaluate shark cartilage as a treatment for cancer. One of its spokesmen has stated that the company is ''unable to find meaningful scientific data to support further investment in pursuing drug status for shark cartilage.''160
Although I am not enthusiastic about either bovine or shark cartilage, if I · had to choose between the two, I would look to bovine since there have been studies showing its benefits as a cancer inhibitor. So far, there has been no such documentation for shark cartilage.
DHEA
DHEA (dehydroepiandrosterone) is an adrenal steroid hormone that functions as a reservoir for other hormones from which the body can draw. It is represented in relatively important amounts in the blood plasma and works from outside the cell. This steroid inhibits enzymes, namely glucose-6-phosphate-dehydrogenase, which plays a pivotal role in the manifestation of cancer metab-

 
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