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virulence (n.)

1660s, from Late Latin virulentia, from Latin virulentus "full of poison" (see virulent). Related: Virulency (1610s).

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Definitions of virulence from WordNet

virulence (n.)
extreme harmfulness (as the capacity of a microorganism to cause disease);
the virulence of the plague
Synonyms: virulency
virulence (n.)
extreme hostility;
the virulence of the malicious old man
Synonyms: virulency
From wordnet.princeton.edu