early 15c., "extract, preparation," from Latin valentia "strength, capacity," from valentem (nominative valens) "strong, stout, vigorous, powerful," present participle of valere "be strong" (from PIE root *wal- "to be strong"). Chemistry sense of "relative combining capacity of an element with other atoms when forming compounds or molecules" is recorded from 1884, from German Valenz (1868), from the Latin word. Related: Valency.