"interior regions," 1680s, from up- + country (n.). As an adjective from 1810; as an adverb from 1864.
upbeat
upbraid
upbringing
upchuck
upcoming
up-country
up-current
update
updraft
upend
*uper
)window.location='https://www.paypal.com/cgi-bin/webscr?cmd=_donations&business=byronic106@yahoo.com&lc=US&item_name=Donation+to +Help+Keep+Etymonline+Free+and+Open&no_note=0&cn=&curency_code=USD&bn=PP-DonationsBF:btn_donateCC_LG.gif:NonHosted'){kind=link}