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transsexual

1957 (adj. and n.), from trans- + sexual, and compare transsexualism.

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Definitions of transsexual from WordNet
1
transsexual (n.)
a person who has undergone a sex change operation;
Synonyms: transexual / transgendered
transsexual (n.)
a person whose sexual identification is entirely with the opposite sex;
Synonyms: transexual
2
transsexual (adj.)
identifying with the opposite gender from the one that one is born with;
From wordnet.princeton.edu