1670s, from Latin quintus "the fifth" (from PIE root *penkwe- "five") + ending from million. Compare billion. In Great Britain, the fifth power of a million (1 followed by 30 zeroes); in U.S. the sixth power of a thousand (1 followed by 18 zeroes).
quintal
quintessence
quintessential
quintet
quintile
quintillion
quintuple
quintuplet
quinzane
quip
quipu