"endow with power," 1817 (Coleridge), from Latin potentia "power, might, force" (from potis "powerful, able, capable; possible," from PIE root *poti- "powerful; lord") + -ate (2) on model of German potenzieren. Specifically as "increase the effect of" (a drug, etc.) by 1917. Related: Potentiated; potentiating; potentiation.
potentiate the drug
potent
potentate
potential
potentiality
potentially
potentiate
potentiometer
pothead
pother
pot-holder
pothole