"one of no faith or religion," 1560s, from Latin nulli-, combining form of nullus "no" (see null) + fides "faith" (from PIE root *bheidh- "to trust, confide, persuade"). As an adjective from 1620s.
nugget
nuisance
nuke
null
nullification
nullifidian
nullify
nulliparous
nullity
numb
number