also nicotin, poisonous volatile alkaloid base found in tobacco leaves, 1819, from French nicotine, earlier nicotiane, from Modern Latin Nicotiana, the formal botanical name for the tobacco plant, named for Jean Nicot (c. 1530-1600), French ambassador to Portugal, who sent tobacco seeds and powdered leaves from Lisbon to France 1561. His name is a diminutive of Nicolas (see Nicholas).