"(self-)important person," 1912, short for Chinook jargon high muck-a-muck, literally "plenty of food" from muckamuck "food" (1847), which is of unknown origin. Also mucky-muck; muckety-muck.
muchly
muchness
mucilage
mucilaginous
muck
muck-a-muck
muckluck
muck-raker
mucose
mucous
mucus