late 14c., of a voice, "pure, clear;" mid-15c., of abstract things, "absolute, sheer;" from Old French mier "pure" (of gold), "entire, total, complete," and directly from Latin merus "unmixed" (of wine), "pure; bare, naked;" figuratively "true, real, genuine," according to some sources probably originally "clear, bright," from PIE *mer- "to gleam, glimmer, sparkle" (source also of Old English amerian "to purify," Old Irish emer "not clear," Sanskrit maricih "ray, beam," Greek marmarein "to gleam, glimmer"). But de Vaan writes "there is no compelling reason to derive 'pure' from 'shining,'" and compares Hittite marri "just so, gratuitously," and suggests the source is a PIE *merH-o- "remaining, pure."
The English sense of "nothing less than, in the fullest sense absolute" (mid-15c., surviving now only in vestiges such as mere folly) existed for centuries alongside the apparently opposite sense of "nothing more than" (1580s, as in a mere dream).