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liftoff (n.)

also lift-off, "vertical take-off of a rocket, etc.," 1956, American English, from the verbal phrase, from lift (v.) + off (adv.). Earlier, of aircraft, simply lift (1879). Figurative use from 1967.

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Definitions of liftoff from WordNet

liftoff (n.)
the initial ascent of a rocket from its launching pad;
From wordnet.princeton.edu