late 14c., "causing relaxation or looseness," from Old French laxatif (13c.), from Medieval Latin laxativus "loosening," from Latin laxat-, past participle stem of laxare "loosen," from laxus "loose, lax" (see lax). The noun meaning "a laxative medicine, a medicine that relieves constipation by relaxing the intestines" is from late 14c.