isolation (n.)a state of separation between persons or groups;
isolation (n.)a feeling of being disliked and alone;
isolation (n.)the act of isolating something; setting something apart from others;
Synonyms: closing off
isolation (n.)(psychiatry) a defense mechanism in which memory of an unacceptable act or impulse is separated from the emotion originally associated with it;
isolation (n.)a country's withdrawal from international politics;
he opposed a policy of American isolation