c. 1600, "neglecting one's duty;" in law, "not in accord with one's moral duty," 1660s, from Medieval Latin inofficiosus "contrary to duty; harmful," from in- "not, opposite of" (see in- (1) + Latin officiosus "dutiful, obliging" (see officious).
Ino
inobservant
inoculate
inoculation
inoffensive
inofficious
inoperable
inoperative
inopportune
inordinate
inorganic