contraction of phrase in as much "to such a degree," which is first attested c. 1300 as in als mikel, a Northern form. Contracted to in asmuch, then, beginning 14c. and especially since 17c., to one word. Meaning "in view of the fact" (followed by as) is from late 14c.
inappropriate
inapt
inaptitude
inarticulate
inartistic
inasmuch
inattention
inattentive
inaudibility
inaudible
inaugural