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hex (v.)

1830, American English, from Pennsylvania German hexe "to practice witchcraft," from German hexen "to hex," related to Hexe "witch," from Middle High German hecse, hexse, from Old High German hagazussa (see hag). Noun meaning "magic spell" is first recorded 1909; earlier it meant "a witch" (1856). Compare Middle English hexte "the devil" (mid-13c.), perhaps originally "sorcerer," probably from Old English haehtis.

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Definitions of hex from WordNet
1
hex (v.)
cast a spell over someone or something; put a hex on someone or something;
Synonyms: bewitch / glamour / witch / enchant / jinx
2
hex (n.)
an evil spell;
Synonyms: jinx / curse / whammy
3
hex (adj.)
of or pertaining to a number system having 16 as its base;
Synonyms: hexadecimal
From wordnet.princeton.edu