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headache (n.)

Old English heafodece; see head (n.) + ache (n.). Colloquial sense of "troublesome problem" is first recorded 1934. Related: Headachy (1705).

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Definitions of headache from WordNet

headache (n.)
something or someone that causes anxiety; a source of unhappiness;
Synonyms: concern / worry / vexation
headache (n.)
pain in the head caused by dilation of cerebral arteries or muscle contractions or a reaction to drugs;
Synonyms: head ache / cephalalgia
From wordnet.princeton.edu