1814, from grape + fruit. Said to have been so called for its taste, or perhaps because it grows in clusters. Perhaps a marketing name; it was known by various names (pomelo, shaddock) before the current one emerged. The fruit itself was known since 1693 (in Hans Sloane's catalogue of Jamaican plants); presumably it originated in Jamaica from chance hybrids between other cultivated citrus. An ornamental plant chiefly at first, not much eaten until late 19c.
granulation
granule
granuloma
granulose
grape
grapefruit
grapeshot
grapevine
-graph
graph
grapheme