"a matron, mistress of a household," early 14c., from good (adj.) + wife (n.). As a term of civility applied to a married woman in humble life, it is a correlative of goodman. "Used like auntie, and mother, and gammer, in addressing or describing an inferior" [Farmer].
good-neighbor
goodness
good-night
goods
good-time
goodwife
goody
gooey
goof
goofball
goofiness