"something dead or about to die, person past recovery, one who is done for in any way," 1836, American English colloquial, from gone + -er (1). From earlier expressions such as gone goose (1830), gone coon, etc.
I'm a goner if this plan doesn't work
Gondal
gondola
gondolier
Gondwana
gone
goner
gonfalon
gong
goniometer
gonna
gono-