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echovirus (n.)

also ECHO virus, 1955, acronym for enteric cytopathogenic human orphan; "orphan" because when discovered they were not known to cause any disease.

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Definitions of echovirus from WordNet

echovirus (n.)
any of a group of viruses associated with various diseases including viral meningitis and mild respiratory disorders and diarrhea in newborn infants;
From wordnet.princeton.edu