1590s, "free from entanglement" (transitive); see dis- + entangle. Related: Disentangled; disentangling; disentanglement.
Can you disentangle the cord?
How can I disentangle myself from her personal affairs?
disenchantment
disencumber
disenfranchise
disengage
disengagement
disentangle
disenthrall
disequilibrium
disestablish
disesteem
disfavor
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