"lose heart, resolution, or hope," 1650s, from Latin despondere "to give up, lose, lose heart, resign; to promise in marriage," etymologically "to promise to give something away," from de "away" (see de-) + spondere "to promise" (see sponsor (n.)). Related: Desponding; despondingly.
The supporters of the Presidential candidate desponded when they learned the early results of the election
despicable
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