1767, of roads, "lying or directed across fields or open country," from cross- + country, or a shortening of across-country. Of flights, from 1909. As a noun, "outdoor distance running as a sport," by 1956.
they liked to race cross-country
the river runs cross-country
the road runs cross-country
crossbones
crossbow
cross-breed
cross-bun
cross-check
cross-country
cross-current
cross-cut
cross-dressing
crossed
cross-examine