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Euphrates

Mesopotamian river, arising in Armenia and flowing to the Persian Gulf, Old English Eufrate, from Greek Euphrates, from Old Persian Ufratu, perhaps from Avestan huperethuua "good to cross over," from hu- "good" + peretu- "ford" (from PIE root *per- (2) "to lead, pass over"). But Kent says "probably a popular etymologizing in O.P. of a local non-Iranian name" ["Old Persian," p.176]. In Akkadian, purattu. Related: Euphratean.

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Definitions of Euphrates from WordNet

Euphrates (n.)
a river in southwestern Asia; flows into the Persian Gulf; was important in the development of several great civilizations in ancient Mesopotamia;
Synonyms: Euphrates River
From wordnet.princeton.edu